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Article

UNC-18 modulates ethanol sensitivity in Caenorhabditis elegans.

Molecular biology of the cell - 1 Jan 2009

Graham Margaret E, Edwards Mark R, Holden-Dye Lindy, Morgan Alan, Burgoyne Robert D, Barclay Jeff W

Abstract excerpt

Acute ethanol exposure affects the nervous system as a stimulant at low concentrations and as a depressant at higher concentrations, eventually resulting in motor dysfunction and uncoordination. A recent genetic study of two mouse strains with varying ethanol preference indicated a correlation with a polymorphism (D216N) in the synaptic protein Munc18-1. Munc18-1 functions in exocytosis via a number of discrete...

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Identifiers

PMID: 18923141
DOI: 10.1091/mbc.e08-07-0689
PMCID: PMC2613081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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