Back to search

Article

(-)-Gossypol inhibition of musashi-mediated forgetting improves memory and age-dependent memory decline in <i>Caenorhabditis elegans</i>

2022-06-21

Abstract excerpt

Musashi RNA-binding proteins retain a pivotal role in stem cell maintenance, tumorigenesis, and nervous system development. Recently, we showed in C. elegans that MSI1 actively promotes forgetting upon associative learning via a 3’UTR-dependent translational expression of the Arp2/3 actin branching complex. Here, we investigated the evolutionary conserved role of MSI proteins and the effect of their pharmacologic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4f7825d2-0b70-541b-8cd6-98653cee28dc
DOI
10.1101/2022.06.20.496809
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
(-)-Gossypol inhibition of musashi-mediated forgetting improves memory and age-dependent memory decline in <i>Caenorhabditis elegans</i>DOI 10.1101/2022.06.20.496809
Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex.Semantic proximity
COMPASS-mediated epigenetic regulation of transcription accelerates forgetting with ageSemantic proximity
A role for α-adducin (ADD-1) in nematode and human memory.Semantic proximity
MSI-1, a neural RNA-binding protein, is involved in male mating behaviour in Caenorhabditis elegans.Semantic proximity
Of FOXes and Forgetful Worms.Semantic proximity
Role of GLR-1 in Age-Dependent Short-Term Memory Decline.Semantic proximity
Dopaminergic Modulation of Short-Term Associative Memory in <i>Caenorhabditis elegans</i>Semantic proximity
Memory consolidation in honey bees is enhanced by down-regulation of <i>Down Syndrome Cell Adhesion Molecule</i> and changes its alternative splicingSemantic proximity
Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway.Semantic proximity
Insulin signaling plays a dual role in Caenorhabditis elegans memory acquisition and memory retrieval.Semantic proximity
The role of Drosophila mushroom body signaling in olfactory memory.Semantic proximity
A Switch from Cycloheximide-Resistant Consolidated Memory to Cycloheximide-Sensitive Reconsolidation and Extinction in<i>Drosophila</i>Semantic proximity
Select a neighboring publication to make it the new centre.