Article
Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily.
Biochemical pharmacology - 1 May 2012
Vandendriessche Thomas, Kopljar Ivan, Jenkins David Paul, Diego-Garcia Elia, Abdel-Mottaleb Yousra, Vermassen Elke, Clynen Elke, Schoofs Liliane, Wulff Heike, Snyders Dirk, Tytgat Jan
Abstract excerpt
Given their medical importance, most attention has been paid toward the venom composition of scorpions of the Buthidae family. Nevertheless, research has shown that the venom of scorpions of other families is also a remarkable source of unique peptidyl toxins. The κ-KTx family of voltage-gated potassium channel (VGPC) scorpion toxins is hereof an example. From the telson of the scorpion Heterometrus laoticus...
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