Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular diversity and evolution of cystine knot toxins of the tarantula Chilobrachys jingzhao.

Cellular and molecular life sciences : CMLS - 1 Aug 2008

Chen J, Deng M, He Q, Meng E, Jiang L, Liao Z, Rong M, Liang S

Abstract excerpt

Cystine knot toxins (CKTs) in spider venoms represent a rich source of novel ligands for varied ion channels. Here, we identified 95 novel putative CKT precursors by analyzing expressed sequence tags of the tarantula Chilobrachys jingzhao venom gland. Phylogenetics analyses revealed one orphan family and six families with sequence similarity to known toxins. To further investigate the relationships of their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ganglia, Spinal

Share to Neurons

Share to Sequence Alignment

Share to Spiders

Share to Structural Homology, Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 18581053
DOI: 10.1007/s00018-008-8135-x
PMCID: PMC11131836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular diversity and evolution of cystine knot toxins of the tarantula Chilobrachys jingzhao.PMID 18581053Read ↗

Molecular Diversity of Peptide Toxins in the Venom of Spider Heteropoda pingtungensis as Revealed by cDNA Library and Transcriptome Sequencing Analysis.Semantic proximity Read ↗

Structural and Functional Diversity of Peptide Toxins from Tarantula Haplopelma hainanum (Ornithoctonus hainana) Venom Revealed by Transcriptomic, Peptidomic, and Patch Clamp Approaches.Semantic proximity Read ↗

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders.Semantic proximity Read ↗

Intragenome Diversity of Gene Families Encoding Toxin-like Proteins in Venomous Animals.Semantic proximity Read ↗

Common architecture of Tc toxins from human and insect pathogenic bacteriaSemantic proximity Read ↗

High conopeptide diversity in Conus tribblei revealed through analysis of venom duct transcriptome using two high-throughput sequencing platforms.Semantic proximity Read ↗

Transcriptome Analysis in Venom Gland of the Predatory Giant Ant Dinoponera quadriceps: Insights into the Polypeptide Toxin Arsenal of HymenopteransSemantic proximity Read ↗

Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.Semantic proximity Read ↗

Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity.Semantic proximity Read ↗

Diversity and evolution of conotoxins based on gene expression profiling of Conus litteratus.Semantic proximity Read ↗

Vexitoxins: a novel class of conotoxin-like venom peptides from predatory gastropods of the genus <i>Vexillum</i>Semantic proximity Read ↗

De Novo Transcriptome Assembly for Venom Gland in Two Spe-Cies of Spiders (Sinopoda Pengi and Trichonephila Clavata)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.