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Article

Novel alpha-KTx sites in the BK channel and comparative sequence analysis reveal distinguishing features of the BK and KV channel outer pore.

Cell biochemistry and biophysics - 1 Jan 2008

Giangiacomo Kathleen M, Becker Jennifer, Garsky Christopher, Schmalhofer William, Garcia Maria L, Mullmann Theodore J

Abstract excerpt

The alpha-KTx peptide toxins inhibit different types of potassium channels by occluding the outer channel pore composed of four identical alpha subunits. The large-conductance, calcium-activated (BK or Slo1) and voltage-dependent (KV) potassium channels differ in their specificity for the different alpha-KTx subfamilies. While many different alpha-KTx subfamilies of different sizes inhibit KV1 channels with high...

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Identifiers

PMID: 18815746
DOI: 10.1007/s12013-008-9026-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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