Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.

Biochemical and biophysical research communications - 21 Nov 2008

Abbas Najwa, Belghazi Maya, Abdel-Mottaleb Yousra, Tytgat Jan, Bougis Pierre E, Martin-Eauclaire Marie-France

Abstract excerpt

In this paper were described the purification, the sequencing, and the immunological and biological characterization of a new Kaliotoxin analog, Aam-KTX, from the venom of the scorpion Androctonus amoreuxi. The toxin effects on three cloned Kv channels (Kv1.1, Kv1.2, and Kv1.3) were investigated in Xenopus oocytes using electrophysiology experiments. The Aam-KTX preference for Kv1.3 channel versus Kv1.2 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Kv1.1 Potassium Channel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oocytes

Share to Potassium Channel Blockers

Share to Protein Conformation

Share to Scorpion Venoms

Share to Xenopus laevis

Source

Identifiers

PMID: 18804453
DOI: 10.1016/j.bbrc.2008.09.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.PMID 18804453Read ↗

Scorpion toxins that block transient currents (I(A)) of rat cerebellum granular cells.Semantic proximity Read ↗

Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily.Semantic proximity Read ↗

Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels.Semantic proximity Read ↗

Evidence for a function-specific mutation in the neurotoxin, parabutoxin 3.Semantic proximity Read ↗

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels.Semantic proximity Read ↗

Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA.Semantic proximity Read ↗

Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.Semantic proximity Read ↗

Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels.Semantic proximity Read ↗

Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.Semantic proximity Read ↗

Different residues in channel turret determining the selectivity of ADWX-1 inhibitor peptide between Kv1.1 and Kv1.3 channels.Semantic proximity Read ↗

A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor.Semantic proximity Read ↗

Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.