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Article

Multilocus analysis of age-related macular degeneration.

European journal of human genetics : EJHG - 1 Sept 2009

Bergeron-Sawitzke Julie, Gold Bert, Olsh Adam, Schlotterbeck Sarah, Lemon Kendal, Visvanathan Kala, Allikmets Rando, Dean Michael

Abstract excerpt

Age-related macular degeneration (AMD) is a late onset vision disorder. Recent studies demonstrate that alterations in complement cascade genes are associated with AMD. Of the three identified complement loci, variants in complement factor H (CFH) have the highest impact as does an independent locus at 10q26. Our matched case-control study using the Age-Related Eye Disease Study (AREDS) cohort confirms and...

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Source

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Identifiers

PMID: 19259132
DOI: 10.1038/ejhg.2009.23
PMCID: PMC2729805

Genes

CFH
APOE
ARMS2
CFB
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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