Article
Genetic and environmental risk factors for age-related macular degeneration in persons 90 years and older.
Investigative ophthalmology & visual science - 25 Mar 2014
Ersoy Lebriz, Ristau Tina, Hahn Moritz, Karlstetter Marcus, Langmann Thomas, Dröge Katharina, Caramoy Albert, den Hollander Anneke I, Fauser Sascha
Abstract excerpt
PURPOSE: We studied associations of genetic polymorphisms in age-related maculopathy susceptibility 2 (ARMS2) and complement factor H (CFH) in nonagenarians with age-related macular degeneration (AMD). METHODS: This case-control study comprised 2737 persons (1204 controls, 1433 AMD cases), including 166 nonagenarians (52 controls, 114 AMD cases). Single nucleotide polymorphisms (SNPs) in the genes ARMS2 and CFH...
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