Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome.

Journal of biomedical science - 2 Feb 2012

Byun Hyang-Min, Heo Kyu, Mitchell Kasey J, Yang Allen S

Abstract excerpt

BACKGROUND: Retrotransposons have been extensively studied in plants and animals and have been shown to have an impact on human genome dynamics and evolution. Their ability to move within genomes gives retrotransposons to affect genome instability. METHODS: we examined the polymorphic inserted AluYa5, evolutionary young Alu, in the progesterone receptor gene to determine the effects of Alu insertion on molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alu Elements
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genome, Human

Share to Genomic Instability

Share to Receptors, Progesterone

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 22300442
DOI: 10.1186/1423-0127-19-13
PMCID: PMC3315731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome.PMID 22300442Read ↗

Evolutionary impact of human Alu repetitive elements.Semantic proximity Read ↗

Genetic and epigenetic variations contributed by Alu retrotransposition.Semantic proximity Read ↗

Retrotransposon life cycle and its impacts on cellular responsesSemantic proximity Read ↗

A systematic screen of breast cancer patients’ exomes for retrotransposon insertions reveals disease associated genesSemantic proximity Read ↗

Active Alu retrotransposons in the human genome.Semantic proximity Read ↗

Transposable elements in cancer and other human diseases.Semantic proximity Read ↗

Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition.Semantic proximity Read ↗

The impact of retrotransposons on human genome evolution.Semantic proximity Read ↗

DNA sequence insertion and evolutionary variation in gene regulation.Semantic proximity Read ↗

Extensive mosaicism by somatic L1 retrotransposition in normal human cellsSemantic proximity Read ↗

The transposable element environment of human genes is associated with histone and expression changes in cancer.Semantic proximity Read ↗

Identification of human-specific AluS elements through comparative genomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.