Article
Genetic and epigenetic variations contributed by Alu retrotransposition.
BMC genomics - 20 Dec 2011
de Andrade Alexandre, Wang Min, Bonaldo Maria F, Xie Hehuang, Soares Marcelo B
Abstract excerpt
BACKGROUND: De novo retrotransposition of Alu elements has been recognized as a major driver for insertion polymorphisms in human populations. In this study, we exploited Alu-anchored bisulfite PCR libraries to identify evolutionarily recent Alu element insertions, and to investigate their genetic and epigenetic variation. RESULTS: A total of 327 putatively recent Alu insertions were identified, altogether...
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