Article
DNA sequence insertion and evolutionary variation in gene regulation.
Proceedings of the National Academy of Sciences of the United States of America - 3 Sept 1996
Britten R J
Abstract excerpt
Current evidence on the long-term evolutionary effect of insertion of sequence elements into gene regions is reviewed, restricted to cases where a sequence derived from a past insertion participates in the regulation of expression of a useful gene. Ten such examples in eukaryotes demonstrate that segments of repetitive DNA or mobile elements have been inserted in the past in gene regions, have been preserved,...
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