Article
Evaluation of Naturally Acquired Antibody Responses to Two Variant Forms of Plasmodium vivax Apical Membrane Antigen-1 in Individuals Living in Areas of Low and Unstable Malaria Transmission of Iran.
Archives of Iranian medicine - 1 Dec 2015
Salavatifar Maryam, Zakeri Sedigheh, Abouie Mehrizi Akram, Mirkhazemi Sedigheh, Dinparast Djadid Navid
Abstract excerpt
BACKGROUND: Acquired antibody responses following natural infection provide valuable information for selection of candidate antigens for malaria vaccines. Apical membrane antigen-1 of Plasmodium vivax (PvAMA-1) has potential as a component of a subunit vaccine for vivax malaria. In addition, genetic diversity in this antigen is responsible for challenges in the development of an effective PvAMA-1 based vaccine....
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