Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice.

American journal of physiology. Renal physiology - 1 Mar 2010

Gurley Susan B, Mach Carrie L, Stegbauer Johannes, Yang Jihong, Snow Kamie P, Hu Ann, Meyer Timothy W, Coffman Thomas M

Abstract excerpt

Previous studies have shown that Akita mice bearing the Ins2(+/C96Y) mutation have significant advantages as a type I diabetes platform for developing models of diabetic nephropathy (DN; Gurley SB, Clare SE, Snow KP, Hu A, Meyer TW, Coffman TM. Am J Physiol Renal Physiol 290: F214-F222, 2006). In view of the critical role for genetic factors in determining susceptibility to DN in humans, we investigated the role...

Topics

Join the communities discussing this publication.

Albuminuria
Blood Glucose
Diabetic Nephropathies
Glomerular Filtration Rate
Hyperglycemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred DBA

Source

Open in PubMed Open full text

Identifiers

PMID: 20042456
DOI: 10.1152/ajprenal.90515.2008
PMCID: PMC2838602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice.PMID 20042456Read ↗

Impact of genetic background on nephropathy in diabetic miceSemantic proximity Read ↗

The impact of genetic background on mouse models of kidney disease.Semantic proximity Read ↗

Assessment of diabetic nephropathy in the Akita mouse.Semantic proximity Read ↗

Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.Semantic proximity Read ↗

Mouse models of diabetic nephropathy.Semantic proximity Read ↗

Mouse Models of Diabetic NephropathySemantic proximity Read ↗

Inflammation and Immunity Pathways Regulate Genetic Susceptibility to Diabetic Nephropathy.Semantic proximity Read ↗

Diabetic nephropathy: of mice and men.Semantic proximity Read ↗

Diabetic modifier QTLs identified in F2 intercrosses between Akita and A/J mice.Semantic proximity Read ↗

A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.Semantic proximity Read ↗

Identification of quantitative trait loci for diabetic nephropathy in KK-Ay/Ta mice.Semantic proximity Read ↗

Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.