Article
HFE gene mutations in patients with alcoholic liver disease. A prospective study from northwestern Poland.
Polskie Archiwum Medycyny Wewnetrznej - 1 Apr 2010
Raszeja-Wyszomirska Joanna, Kurzawski Grzegorz, Zawada Iwona, Suchy Janina, Lubinski Jan, Milkiewicz Piotr
Abstract excerpt
INTRODUCTION: Hereditary hemochromatosis has been linked with C282Y and H63D mutations of the HFE gene encoding human hemochromatosis protein. It is genetic disorder of iron metabolism, leading to iron accumulation and increased liver fibrosis. The association between alcoholic liver disease (ALD) and HFE gene mutations remains unclear and requires clarification. OBJECTIVES: The aim of the study was to determine...
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