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Article

The role of iron overload and HFE gene mutations in the era of pegylated interferon and ribavirin treatment of chronic hepatitis C.

Medical science monitor : international medical journal of experimental and clinical research - 1 Mar 2010

Sikorska Katarzyna, Stalke Piotr, Izycka-Swieszewska Ewa, Romanowski Tomasz, Bielawski Krzysztof Piotr

Abstract excerpt

BACKGROUND: Iron overload observed in chronic hepatitis C (CHC) has been suggested to be one of the negative prognostic factors influencing liver disease progression and failure of treatment with recombinant interferon in monotherapy or in combination with ribavirin. The aim of this study was to assess occurrence of iron overload in relation to polymorphism of the HFE and the influence of both these factors on...

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Source

Identifiers

PMID: 20190684

Genes

HFE

Provenance

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