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Article

Influence of MDR1 gene codon 3435 polymorphisms on outcome of platinum-based chemotherapy for advanced non small cell lung cancer.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Yan Peng-wei, Huang Xin-en, Yan Feng, Xu Lin, Jiang Yong

Abstract excerpt

OBJECTIVE: To evaluate the influence of multi-drug resistance 1 (MDR1) gene codon 3435 polymorphisms on response to platinum-based chemotherapeutic regimens for advanced non small cell lung cancer (NSCLC). METHODS: Responses and overall survival were evaluated in a series of patients presenting between March 1, 2005 and December 31, 2010. MDR1 gene C3435T polymorphisms were genotyped using peripheral blood with...

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PMID: 22296372

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