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MDR1 single nucleotide polymorphism C3435T in Turkish patients with non-small-cell lung cancer.

Gene - 15 Sept 2012

Dogu Gamze Gokoz, Kargi Aysegul, Turgut Sebahat, Ayada Ceylan, Taskoylu Burcu Yapar, Demiray Gokcen, Yaren Arzu, Ozlu Can, Temel Sahin, Ergin Ahmet

Abstract excerpt

We assessed whether single nucleotide polymorphisms (SNPs) in MDR1 gene C3435T predicted the outcome of platinum-based chemotherapies and survival in our non small cell lung cancer (NSCLC) patients. A total of 79 non-small cell lung cancer patients were enrolled to study. We determined the MDR1 C3435T single nucleotide gene polymorphisms. Median age was 60years: 91.7% male, 8.9% female. We found that CC, CT, TT...

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PMID: 22766400
DOI: 10.1016/j.gene.2012.06.057

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