Article
Polymorphisms of ERCC1 C118T/C8092A and MDR1 C3435T predict outcome of platinum-based chemotherapies in advanced non-small cell lung cancer: a meta-analysis.
Archives of medical research - 1 Jul 2011
Wei Hai-Bo, Lu Xiang-Shi, Shang Li-Hua, Xu Gang, Hu Jing, Che De-Hai, Liu Fang, Wu Ying, Zhang Guang-Mei, Yu Yan
Abstract excerpt
BACKGROUND AND AIMS: With great progress made in individualized chemotherapy, pharmacogenetics is gradually put on the agenda. We performed this meta-analysis to compare outcome to platinum-based chemotherapies in advanced non-small cell lung cancer (NSCLC) with different ERCC1 C118T/C8092A and MDR1 C3435T polymorphisms. METHODS: Relevant studies were identified according to search strategy in this meta-analysis....
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