Article
Genetic landscape of sporadic vestibular schwannoma.
Journal of neurosurgery - 1 Mar 2018
Håvik Aril Løge, Bruland Ove, Myrseth Erling, Miletic Hrvoje, Aarhus Mads, Knappskog Per-Morten, Lund-Johansen Morten
Abstract excerpt
OBJECTIVE Vestibular schwannoma (VS) is a benign tumor with associated morbidities and reduced quality of life. Except for mutations in NF2, the genetic landscape of VS remains to be elucidated. Little is known about the effect of Gamma Knife radiosurgery (GKRS) on the VS genome. The aim of this study was to characterize mutations occurring in this tumor to identify new genes and signaling pathways important for...
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