Article
CpG island hypermethylation of the neurofibromatosis type 2 (NF2) gene is rare in sporadic vestibular schwannomas.
Neuropathology and applied neurobiology - 1 Oct 2010
Kullar P J, Pearson D M, Malley D S, Collins V P, Ichimura K
Abstract excerpt
AIMS: Loss of both wild-type copies of the neurofibromatosis type 2 (NF2) gene is found in both sporadic and neurofibromatosis type 2-associated vestibular schwannomas (VS). Previous studies have identified a subset of VS with no loss or mutation of NF2. We hypothesized that methylation of NF2 re...
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