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Article

IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2009

Nobusawa Sumihito, Watanabe Takuya, Kleihues Paul, Ohgaki Hiroko

Abstract excerpt

PURPOSE: To establish the frequency of IDH1 mutations in glioblastomas at a population level, and to assess whether they allow reliable discrimination between primary (de novo) glioblastomas and secondary glioblastomas that progressed from low-grade or anaplastic astrocytoma. EXPERIMENTAL DESIGN: We screened glioblastomas from a population-based study for IDH1 mutations and correlated them with clinical data and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19755387
DOI: 10.1158/1078-0432.CCR-09-0715

Genes

IDH1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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