Article
Association of IL1R polymorphism with HLA-B27 positive in Iranian patients with ankylosing spondylitis.
European cytokine network - 1 Dec 2011
Mahmoudi M, Amirzargar A A, Jamshidi A R, Farhadi E, Noori S, Avraee M, Nazari B, Nicknam M H
Abstract excerpt
Ankylosing spondylitis (AS) is one of the most common causes of inflammatory arthritis, with an estimated prevalence of 0.1-0.9%. Genetic factors have been strongly implicated in its aetiology, and heritability as assessed by twin studies has been estimated to be >90%. HLA- B27 is almost essentia...
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