Article
Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis.
Annals of the rheumatic diseases - 1 Sept 2008
Sims A-M, Timms A E, Bruges-Armas J, Burgos-Vargas R, Chou C-T, Doan T, Dowling A, Fialho R N, Gergely P, Gladman D D, Inman R, Kauppi M, Kaarela K, Laiho K, Maksymowych W, Pointon J J, Rahman P, Reveille J D, Sorrentino R, Tuomilehto J, Vargas-Alarcon G, Wordsworth B P, Xu H, Brown M A
Abstract excerpt
OBJECTIVES: The aim of the current study was to determine the contribution of interleukin (IL)1 gene cluster polymorphisms previously implicated in susceptibility for ankylosing spondylitis (AS) to AS susceptibility in different populations worldwide. METHODS: Nine polymorphisms in the IL1 gene c...
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