Article
Determination of IL-23 receptor gene polymorphism in Iranian patients with ankylosing spondylitis.
European cytokine network - 1 Mar 2014
Daryabor Gholamreza, Mahmoudi Mahdi, Jamshidi Ahmadreza, Nourijelyani Keramat, Amirzargar Aliakbar, Ahmadzadeh Nooshin, Farhadi Elham, Nicknam Mohammad Hossein
Abstract excerpt
INTRODUCTION: The result of recent genome-wide association studies revealed that, in addition to HLA-B27, a few non-HLA genes are associated with susceptibility to ankylosing spondylitis (AS) in Caucasian populations. According to these studies, IL-23R is one of the genes that is associated with AS. In this study, we evaluated five important single nucleotide polymorphisms (SNPs) of the IL-23R gene which confers...
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