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Article

Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis.

PloS one - 1 Jan 2011

Wei James Cheng-Chung, Yen Jeng-Hsien, Juo Suh-Hang Hank, Chen Wei-Chiao, Wang Yu-Shiuan, Chiu Yi-Ching, Hsieh Tusty-Jiuan, Guo Yuh-Cherng, Huang Chun-Huang, Wong Ruey-Hong, Wang Hui-Po, Tsai Ke-Li, Wu Yang-Chang, Chang Hsueh-Wei, Hsi Edward, Chang Wei-Pin, Chang Wei-Chiao

Abstract excerpt

Ankylosing spondylitis (AS) is a chronic inflammation of the sacroiliac joints, spine and peripheral joints. The aetiology of ankylosing spondylitis is still unclear. Previous studies have indicated that genetics factors such as human leukocyte antigen HLA-B27 associates to AS susceptibility. We carried out a case-control study to determine whether the genetic polymorphisms of ORAI1 gene, a major component of...

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Source

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Identifiers

PMID: 21674042
DOI: 10.1371/journal.pone.0020426
PMCID: PMC3106015

Genes

ORAI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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