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Article

The origin and evolution of variable number tandem repeat of CLEC4M gene in the global human population.

PloS one - 1 Jan 2012

Li Hui, Wang Jia-Xin, Wu Dong-Dong, Wang Hua-Wei, Tang Nelson Leung-Sang, Zhang Ya-Ping

Abstract excerpt

CLEC4M is a C-type lectin gene serving as cell adhesion receptor and pathogen recognition receptor. It recognizes several pathogens of important public health concern. In particular, a highly polymorphic variable number tandem repeat (VNTR) at the neck-region of CLEC4M had been associated with genetic predisposition to some infectious diseases. To gain insight into the origin and evolution of this VNTR in CLEC4M,...

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PMID: 22279577
DOI: 10.1371/journal.pone.0030268
PMCID: PMC3261175

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