Article
Interleukin-37 gene variants segregated anciently coexist during hominid evolution.
European journal of human genetics : EJHG - 1 Oct 2015
Kang Bin, Cheng Shimeng, Peng Jinbiao, Yan Jingjing, Zhang Shuye
Abstract excerpt
IL37 is a member of IL-1 cytokine family but conveys anti-inflammatory functions. The biological characteristic and genetic heterogeneity of IL37 are not fully understood yet. Here using the whole-genome sequencing data from 1000 Genomes Project, we performed population and evolutionary genetic analysis of human IL37 gene. First, 2184 IL37 gene sequences from different human populations were retrieved. The IL37...
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