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Article

Genetic variation in the C-type lectin receptor CLEC4M in type 1 von Willebrand Disease patients.

PloS one - 1 Jan 2018

Manderstedt Eric, Lind-Halldén Christina, Lethagen Stefan, Halldén Christer

Abstract excerpt

von Willebrand factor (VWF) levels in healthy individuals and in patients with type 1 von Willebrand disease (VWD) are influenced by genetic variation in several genes, e.g. VWF, ABO, STXBP5 and CLEC4M. This study aims to screen comprehensively for CLEC4M variants and investigate their association with type 1 VWD in the Swedish population. In order to screen for CLEC4M variants, the CLEC4M gene region was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29389944
DOI: 10.1371/journal.pone.0192024
PMCID: PMC5794141

Genes

VWF
ABO
STXBP5

Variants

Provenance

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