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<i>In silico</i> analyses of CD14 molecule reveals significant evolutionary diversity potentially associated with speciation and variable immune response in mammals

2019-05-17

Abstract excerpt

Cluster differentiation gene (CD14) is a family of monocyte differentiating genes that works in conjunction with lipopolysaccharide binding protein (LBP), forming a complex with TLR4 or LY96 to mediate innate immune response to pathogens. In this paper, we used different computational methods to elucidate the evolution of CD14 gene coding region in 14 mammalian species. Our analyses identified leucine rich repeats...

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Literature Corpus work
031a6b4a-ba87-58d6-902a-b579272911aa
DOI
10.7287/peerj.preprints.27668v2
Open publication

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