Article
14-3-3ζ interacts with stat3 and regulates its constitutive activation in multiple myeloma cells.
PloS one - 1 Jan 2012
Zhang Jia, Chen Fangjin, Li Wenliang, Xiong Qian, Yang Mingkun, Zheng Peng, Li Chongyang, Pei Jianfeng, Ge Feng
Abstract excerpt
The 14-3-3 proteins are a family of regulatory signaling molecules that interact with other proteins in a phosphorylation-dependent manner and function as adapter or scaffold proteins in signal transduction pathways. One family member, 14-3-3ζ, is believed to function in cell signaling, cycle control, and apoptotic death. A systematic proteomic analysis done in our laboratory has identified signal transducers and...
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