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Article

Biological Hallmarks and Emerging Strategies to Target STAT3 Signaling in Multiple Myeloma

10 Mar 2022

Abstract excerpt

Multiple myeloma (MM) is the second most common hematological malignancy, characterized by an abnormal accumulation of plasma cells in the bone marrow. Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription factor that modulates the transcription of multiple genes to regulate various principal biological functions, for example, cell proliferation and survival, stemness,...

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PMID: 35326392
DOI: 10.3390/cells11060941

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