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Article

A biochemical characterization of the DNA binding activity of the response regulator VicR from Streptococcus mutans.

PloS one - 1 Jan 2014

Ayala Eduardo, Downey Jennifer S, Mashburn-Warren Lauren, Senadheera Dilani B, Cvitkovitch Dennis G, Goodman Steven D

Abstract excerpt

Two-component systems (TCSs) are ubiquitous among bacteria and are among the most elegant and effective sensing systems in nature. They allow for efficient adaptive responses to rapidly changing environmental conditions. In this study, we investigated the biochemical characteristics of the Streptococcus mutans protein VicR, an essential response regulator that is part of the VicRK TCS. We dissected the DNA...

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Identifiers

PMID: 25229632
DOI: 10.1371/journal.pone.0108027
PMCID: PMC4168254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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