Article
Context effects in the formation of deletions in Escherichia coli.
Genetics - 1 Sept 1990
Kazic T, Berg D E
Abstract excerpt
We have examined the frequency with which identical deletions are formed in different chromosomal contexts. A panel of six mutant bla genes containing palindrome/direct repeat structures were moved from pBR322 to three locations: at lambda att, at chromosomal lac, and at F'lac. Deletion of the palindromes and one of the direct repeats results in reversion to Ampr. The frequency of deletion for all alleles...
Topics
- Alleles
- Chromosome Deletion
- Escherichia coli
- Genes, Bacterial
- Mutation
- Plasmids
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping