Article
Rates and consequences of recombination between rRNA operons.
Journal of bacteriology - 1 Feb 2003
Hashimoto Joel G, Stevenson Bradley S, Schmidt Thomas M
Abstract excerpt
A mutant strain of Escherichia coli was created by inserting a cassette encoding sucrose sensitivity and neomycin resistance (sacB-neo) into the small-subunit rRNA-encoding gene rrs in the rrnB operon. During growth in a complex medium, the cassette was lost from the population, and a complete rrs gene was restored at a rate of 5 x 10(-9) per cell division. Repair of this lesion required flanking regions of DNA...
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