Limits to the role of palindromy in deletion formation.

Abstract excerpt

We tested the effect of palindromy on deletion formation. This involved a study of reversion of insertion mutations in the pBR322 amp gene at a site where deletions end either in 9-bp direct repeats or in adjoining 4-bp direct repeats. Inserts of palindromic DNAs ranging from 10 to more than 26 bp and related nonpalindromic DNAs were compared. The frequency of deletions (selected as Ampr revertants) was...

Topics

• Alleles
• Base Sequence
• Chromosome Deletion
• DNA Replication
• DNA Transposable Elements
• DNA, Bacterial
• Escherichia coli
• Genes, Bacterial
• Models, Genetic
• Molecular Sequence Data
• Mutagenesis, Insertional