Complementation analysis of mutants defective in different steps of HBV reverse transcription.

doi:10.1007/BF02779921

Back to search

Article

Complementation analysis of mutants defective in different steps of HBV reverse transcription.

Gastroenterologia Japonica - 1 Sept 1990

Schaller H, Radziwill G

Abstract excerpt

The HBV P gene encodes a multifunctional polyprotein which contains the major enzymatic activities required for hepadnaviral reverse transcription (protein primer, DNA polymerase, and RNase H). Mutant HBV genomes unable to synthesize fully functional P gene products were analysed for their potent...

Topics

Defective Viruses
Genes, Viral
Genetic Complementation Test
Hepatitis B virus
Mutation
Transcription, Genetic
Viral Proteins
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.