Article
Co-replication analyses of naturally occurring defective hepatitis B virus variants with wild-type.
Virology - 15 Mar 2008
Märschenz Stefanie, Brinckmann Anja, Nürnberg Peter, Krüger Detlev H, Günther Stephan, Meisel Helga
Abstract excerpt
Complex hepatitis B virus (HBV) variants with mutations in core promoter (Cp) plus deletions in the C gene and/or preS region--that are associated with development of liver cirrhosis in renal transplant recipients--show a drastically changed phenotype with altered transcription and disturbed surface and core protein expression. Here, we analyzed the replication phenotype of six different defective variant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
