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Article

Multiplex detection and SNP genotyping in a single fluorescence channel.

PloS one - 1 Jan 2012

Fu Guoliang, Miles Andrea, Alphey Luke

Abstract excerpt

Probe-based PCR is widely used for SNP (single nucleotide polymorphism) genotyping and pathogen nucleic acid detection due to its simplicity, sensitivity and cost-effectiveness. However, the multiplex capability of hydrolysis probe-based PCR is normally limited to one target (pathogen or allele) per fluorescence channel. Current fluorescence PCR machines typically have 4-6 channels. We present a strategy...

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Identifiers

PMID: 22272339
DOI: 10.1371/journal.pone.0030340
PMCID: PMC3260291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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