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Article

A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasia.

Cancer prevention research (Philadelphia, Pa.) - 1 Mar 2012

Piyathilake Chandrika J, Badiga Suguna, Kabagambe Edmond K, Azuero Andres, Alvarez Ronald D, Johanning Gary L, Partridge Edward E

Abstract excerpt

There is a paucity of research examining the relationships between dietary patterns and risk of developing precancerous lesions as well as biomarkers associated with such dietary patterns. The purpose of the current study was to identify dietary patterns that are associated with higher grades of cervical intraepithelial neoplasia (CIN 2+) and to determine whether these dietary patterns are associated with the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Leukocytes, Mononuclear

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Source

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Identifiers

PMID: 22262813
DOI: 10.1158/1940-6207.CAPR-11-0387
PMCID: PMC5547882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasia.PMID 22262813Read ↗

DNA Methylation in Cancer: Epigenetic View of Dietary and Lifestyle FactorsSemantic proximity Read ↗

LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasiaSemantic proximity Read ↗

A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era.Semantic proximity Read ↗

A Lower Degree of PBMC L1 Methylation Is Associated with Excess Body Weight and Higher HOMA-IR in the Presence of Lower Concentrations of Plasma FolateSemantic proximity Read ↗

Folate deficiency modifies the risk of CIN3+ associated with DNA methylation levels: a nested case–control study from the ASCUS-COL trialSemantic proximity Read ↗

Folate and vitamin B12 may play a critical role in lowering the HPV 16 methylation-associated risk of developing higher grades of CIN.Semantic proximity Read ↗

Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3.Semantic proximity Read ↗

A nested case‐control study of dietary factors and the risk of incident cytological abnormalities of the cervixSemantic proximity Read ↗

Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12.Semantic proximity Read ↗

A higher degree of methylation of the HPV 16 E6 gene is associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasia.Semantic proximity Read ↗

Folate Status and Aberrant DNA Methylation Are Associated With HPV Infection and Cervical PathogenesisSemantic proximity Read ↗

Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia.Semantic proximity Read ↗

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