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Folate Status and Aberrant DNA Methylation Are Associated With HPV Infection and Cervical Pathogenesis

1 Oct 2009

Abstract excerpt

Aberrant DNA methylation is a recognized feature of human cancers, and folate is directly involved in DNA methylation via one-carbon metabolism. Previous reports also suggest that folate status is associated with the natural history of human papillomavirus (HPV) infection. A cross-sectional study was conducted to test the hypothesis that folate status and aberrant DNA methylation show a progressive change across...

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PMID: 19755648
DOI: 10.1158/1055-9965.epi-09-0493

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