Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis.

Journal of neuroimmunology - 1 Apr 2012

Stojković Ljiljana, Djurić Tamara, Stanković Aleksandra, Dinčić Evica, Stančić Olja, Veljković Nevena, Alavantić Dragan, Zivković Maja

Abstract excerpt

We investigated the association of CX3CR1 genotypes/haplotypes with MS and performed the prediction analysis of protein sequence variants' effects on CX3CL1/CX3CR1 interaction. We found no association of CX3CR1 with MS susceptibility. Frequency of I(249)T(280) haplotype was significantly lower in SP compared to RR patients (RR>10 years, OR=0.30, 95%CI=0.11-0.79, p=0.01; OR=0.53, 95%CI=0.18-1.56, p=0.2, in SP<10...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CX3C Chemokine Receptor 1
Share to Isoleucine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methionine

Share to Multiple Sclerosis, Chronic Progressive

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Receptors, Chemokine

Share to Threonine

Share to Valine

Source

Identifiers

PMID: 22261545
DOI: 10.1016/j.jneuroim.2011.12.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis.PMID 22261545Read ↗

Fractalkine gene receptor polymorphism in patients with multiple sclerosis.Semantic proximity Read ↗

CX3CR1 is a modifying gene of survival and progression in amyotrophic lateral sclerosis.Semantic proximity Read ↗

A common genetic variant rs2821557 in KCNA3 is linked to the severity of multiple sclerosis.Semantic proximity Read ↗

Role of the fractalkine receptor CX3CR1 polymorphisms V249I and T280M as risk factors for early-onset coronary artery disease in patients with no classic risk factors.Semantic proximity Read ↗

Polymorphism of the fractalkine receptor CX3CR1 and systemic sclerosis-associated pulmonary arterial hypertension.Semantic proximity Read ↗

Two polymorphisms in the Fractalkine receptor CX3CR1 gene influence the development of atherosclerosis: a meta-analysis.Semantic proximity Read ↗

Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease.Semantic proximity Read ↗

Prospective study of common variants in CX3CR1 and risk of macular degeneration: pooled analysis from 5 long-term studies.Semantic proximity Read ↗

Association of the CX3CR1-V249I Variant with Neurofibrillary Pathology Progression in Late-Onset Alzheimer's Disease.Semantic proximity Read ↗

Effects of fractalkine receptor variants on common carotid artery intima-media thickness.Semantic proximity Read ↗

T280M and V249I polymorphisms of fractalkine receptor CX3CR1 and ischemic cerebrovascular disease.Semantic proximity Read ↗

Opposite effects of CX3CR1 receptor polymorphisms V249I and T280M on the development of acute coronary syndrome. A possible implication of fractalkine in inflammatory activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.