Article
T280M and V249I polymorphisms of fractalkine receptor CX3CR1 and ischemic cerebrovascular disease.
Neuroscience letters - 10 Feb 2005
Hattori Hidenori, Ito Daisuke, Tanahashi Norio, Murata Mitsuru, Saito Ikuo, Watanabe Kiyoaki, Suzuki Norihiro
Abstract excerpt
The contribution to atherosclerosis of two CX3CR1 single nucleotide polymorphisms, V249I and T280M has been recently reported. The atherosclerosis of intracranial vessels is thought to be the major pathological mechanism of ischemic stroke. In this study, we investigated the risk of ischemic stroke associated with fractalkine receptor CX3CR1 polymorphisms. We investigated the T280M and V249I mutations in the...
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