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Article

A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort.

Genes and immunity - 1 Jun 2012

Gathungu G, Zhang C K, Zhang W, Cho J H

Abstract excerpt

Interferon regulatory factor 5 (IRF5) located on human chromosome 7q32 is associated with many chronic inflammatory disorders. IRF5 is the key regulator of proinflammatory cytokines and type I interferons. We surveyed two cohorts of inflammatory bowel disease (IBD) patients from a North American Consortium. Six single-nucleotide polymorphisms and a 5-base-pair (bp) insertion-deletion (CGGGG indel)polymorphism...

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PMID: 22257839
DOI: 10.1038/gene.2011.90
PMCID: PMC3809990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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