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Article

Genetic susceptibility to tobacco-related cancer.

Oncogene - 23 Aug 2004

Wu Xifeng, Zhao Hua, Suk Rebecca, Christiani David C

Abstract excerpt

Although cigarette smoking is the dominant risk factor for several epithelial cancers, only a small fraction of individuals with tobacco exposure develop cancer. The underlying hypothesis is that genetic factors may render certain smokers more susceptible to cancer than others. Genetic alterations in critical regulatory pathways may predispose cells to carcinogenesis. These pathways include regulation of...

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PMID: 15322521
DOI: 10.1038/sj.onc.1207811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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