Article
Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients.
Journal of hepatology - 1 Mar 2011
Sarrazin Christoph, Susser Simone, Doehring Alexandra, Lange Christian Markus, Müller Tobias, Schlecker Christina, Herrmann Eva, Lötsch Jörn, Berg Thomas
Abstract excerpt
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated with the response to interferon-alfa/ribavirin therapy in hepatitis C virus (HCV) genotype 1-infected patients. The importance of three IL28B single nucleotide polymorphisms (rs8099917, rs12980275 and rs12979860) for HCV genotype 2/3-infected patients is unknown. METHODS: In patients with chronic hepatitis C genotype 2/3...
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