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Paneth cell development in the neonatal gut: pathway regulation, development, and relevance to necrotizing enterocolitis

17 May 2023

Abstract excerpt

Paneth cells (PCs) are intestinal epithelial cells (IECs) that contain eosinophilic granules, which are located in Lieberkühn crypts. An increasing number of animal and human experiments have indicated that PCs are involved in the progression of a variety of intestinal as well as systemic inflammatory responses including necrotizing enterocolitis (NEC). NEC is an enteric acquired disease with high mortality that...

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PMID: 37266449
DOI: 10.3389/fcell.2023.1184159

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