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Article

Multiple members of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family are essential for viability in Drosophila.

The Journal of biological chemistry - 17 Feb 2012

Tran Duy T, Zhang Liping, Zhang Ying, Tian E, Earl Lesley A, Ten Hagen Kelly G

Abstract excerpt

Mucin-type O-glycosylation represents a major form of post-translational modification that is conserved across most eukaryotic species. This type of glycosylation is initiated by a family of enzymes (GalNAc-Ts in mammals and PGANTs in Drosophila) whose members are expressed in distinct spatial and temporal patterns during development. Previous work from our group demonstrated that one member of this family is...

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Identifiers

PMID: 22157008
DOI: 10.1074/jbc.M111.306159
PMCID: PMC3285305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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