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Article

Polymorphisms in the lcrV gene of Yersinia enterocolitica and their effect on plague protective immunity.

Infection and immunity - 1 Apr 2012

Miller Nathan C, Quenee Lauriane E, Elli Derek, Ciletti Nancy A, Schneewind Olaf

Abstract excerpt

Current efforts to develop plague vaccines focus on LcrV, a polypeptide that resides at the tip of type III secretion needles. LcrV-specific antibodies block Yersinia pestis type III injection of Yop effectors into host immune cells, thereby enabling phagocytes to kill the invading pathogen. Earlier work reported that antibodies against Y. pestis LcrV cannot block type III injection by Yersinia enterocolitica...

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Source

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Identifiers

PMID: 22252870
DOI: 10.1128/IAI.05637-11
PMCID: PMC3318405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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