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Article

DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4)

17 Jan 2012

Abstract excerpt

BACKGROUND: Vascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by...

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PMID: 22251800
DOI: 10.1186/1471-2407-12-19

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