Article
Vascular endothelial growth factor overexpression in myelodysplastic syndrome bone marrow cells: biological and clinical implications.
Leukemia & lymphoma - 1 Jul 2017
Invernizzi Rosangela, Travaglino Erica, Della Porta Matteo Giovanni, Malcovati Luca, Gallì Anna, Bastia Raffaella, Ciola Mariella, Ambaglio Ilaria, Boveri Emanuela, Rosti Vittorio, Cazzola Mario
Abstract excerpt
In myelodysplastic syndrome (MDS), vascular endothelial growth factor (VEGF) may have regulatory effects on the hematopoietic system and contribute to disease progression. We analyzed by immunocytochemistry VEGF expression in bone marrow (BM) cells from 188 patients with MDS and 96 non-hemopathic subjects. We also measured VEGF BM plasma levels and in vitro VEGF release. Our aims were to evaluate whether VEGF...
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